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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TBC1D2 Antibody (Center)   

TBC1D2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBC1D2 Antibody (Center) AP18590C
    TBC1D2 Antibody (Center) (Cat. #AP18590c) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TBC1D2 antibody detected the TBC1D2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BYX2
Other Accession NP_060891.3
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 105414 Da
Antigen Region 438-465 aa
Additional Information
Gene ID 55357
Other Names TBC1 domain family member 2A, Armus, Prostate antigen recognized and identified by SEREX 1, PARIS-1, TBC1D2, PARIS1, PP8997, TBC1D2A
Target/Specificity This TBC1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-465 amino acids from the Central region of human TBC1D2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBC1D2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBC1D2
Synonyms PARIS1, PP8997, TBC1D2A
Function Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
Cellular Location Cytoplasm. Cytoplasmic vesicle. Cell junction
Tissue Location Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level).
Research Areas
Citations (0)

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TBC1D2 acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivativation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.


Letra, A., et al. Am. J. Med. Genet. A 152A (7), 1701-1710 (2010) :
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Zhou, Y., et al. Biochem. Biophys. Res. Commun. 290(2):830-838(2002)

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$ 295.00
$ 99.00
Cat# AP18590C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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