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REEP5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q00765 |
| Other Accession | NP_005660.4 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 21493 Da |
| Antigen Region | 141-169 aa |
| Gene ID | 7905 |
|---|---|
| Other Names | Receptor expression-enhancing protein 5, Polyposis locus protein 1, Protein TB2, REEP5, C5orf18, DP1, TB2 |
| Target/Specificity | This REEP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the C-terminal region of human REEP5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | REEP5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | REEP5 |
|---|---|
| Synonyms | C5orf18, DP1, TB2 |
| Function | Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q60870}; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network (PubMed:23969831). In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity) {ECO:0000250|UniProtKB:Q60870, ECO:0000269|PubMed:23969831} |
| Tissue Location | Expressed in heart (at protein level) (PubMed:32075961). Expressed in circumvallate papillae and testis (PubMed:16720576). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
REEP5 may promote functional cell surface expression of olfactory receptors.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lesch, K.P., et al. J Neural Transm 115(11):1573-1585(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Shin, S.M., et al. Gastroenterology 130(7):2074-2086(2006)
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