|Application ||WB, E|
|Calculated MW||38134 Da|
|Antigen Region||39-65 aa|
|Other Names||Ileal sodium/bile acid cotransporter, Apical sodium-dependent bile acid transporter, ASBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, IBAT, ISBT, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, ileal, Solute carrier family 10 member 2, Slc10a2, Ntcp2|
|Target/Specificity||This Mouse Slc10a2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the N-terminal region of mouse Slc10a2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Slc10a2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Slc10a2 plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity).
Halpern, M.D., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G623-G631 (2010) :
Festing, M.H., et al. Genesis 47(12):858-863(2009)
Cheng, X., et al. Drug Metab. Dispos. 37(11):2178-2185(2009)
Sarwar, Z., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (3), G532-G538 (2009) :
Saeki, T., et al. Biosci. Biotechnol. Biochem. 73(7):1535-1540(2009)
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