|Application ||WB, E|
|Calculated MW||38134 Da|
|Antigen Region||39-65 aa|
|Other Names||Ileal sodium/bile acid cotransporter, Apical sodium-dependent bile acid transporter, ASBT, Ileal Na(+)/bile acid cotransporter, Ileal sodium-dependent bile acid transporter, IBAT, ISBT, Na(+)-dependent ileal bile acid transporter, Sodium/taurocholate cotransporting polypeptide, ileal, Solute carrier family 10 member 2, Slc10a2, Ntcp2|
|Target/Specificity||This Mouse Slc10a2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-65 amino acids from the N-terminal region of mouse Slc10a2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Slc10a2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Slc10a2 plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (By similarity).
Halpern, M.D., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (3), G623-G631 (2010) :
Festing, M.H., et al. Genesis 47(12):858-863(2009)
Cheng, X., et al. Drug Metab. Dispos. 37(11):2178-2185(2009)
Sarwar, Z., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 297 (3), G532-G538 (2009) :
Saeki, T., et al. Biosci. Biotechnol. Biochem. 73(7):1535-1540(2009)
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