|Application ||WB, E|
|Other Accession||Q95KI3, NP_620411.2|
|Calculated MW||41176 Da|
|Antigen Region||259-289 aa|
|Other Names||Endothelial cell-selective adhesion molecule, ESAM|
|Target/Specificity||This ESAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-289 amino acids from the C-terminal region of human ESAM.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ESAM Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can mediate aggregation most likely through a homophilic molecular interaction.|
|Cellular Location||Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in endothelial cells.|
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Provided below are standard protocols that you may find useful for product applications.
ESAM can mediate aggregation most likely through a homophilic molecular interaction (By similarity).
Rohatgi, A., et al. Arterioscler. Thromb. Vasc. Biol. 29(10):1684-1690(2009)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Nasdala, I., et al. J. Biol. Chem. 277(18):16294-16303(2002)
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