|Application ||WB, E|
|Other Accession||P97838, Q6PFD5, NP_001073887.1|
|Calculated MW||106040 Da|
|Antigen Region||172-199 aa|
|Other Names||Disks large-associated protein 3, DAP-3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95-associated protein 3, SAPAP3, DLGAP3, DAP3|
|Target/Specificity||This DLGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-199 amino acids from the N-terminal region of human DLGAP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DLGAP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.|
|Cellular Location||Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Cell junction, synapse. Note=Postsynaptic density of neuronal cells.|
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Provided below are standard protocols that you may find useful for product applications.
DLGAP3 may play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Bienvenu, O.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (5), 710-720 (2009) :
Zuchner, S., et al. Mol. Psychiatry 14(1):6-9(2009)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Bongiorno-Borbone, L., et al. Biochem. Biophys. Res. Commun. 337(2):641-646(2005)
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