EAF1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q96JC9 |
Other Accession | Q9D4C5, NP_149074.3 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 29042 Da |
Antigen Region | 58-85 aa |
Gene ID | 85403 |
---|---|
Other Names | ELL-associated factor 1, EAF1 |
Target/Specificity | This EAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-85 amino acids from the Central region of human EAF1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | EAF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | EAF1 |
---|---|
Function | Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. |
Cellular Location | Nucleus speckle. Nucleus, Cajal body |
Tissue Location | Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus |
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Provided below are standard protocols that you may find useful for product applications.
Background
EAF1 acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
References
Wan, X., et al. PLoS ONE 5 (2), E9118 (2010) :
Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Xiao, W., et al. Prostate 66(1):1-12(2006)
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