|Application ||WB, E|
|Other Accession||Q9D4C5, NP_149074.3|
|Calculated MW||29042 Da|
|Antigen Region||58-85 aa|
|Other Names||ELL-associated factor 1, EAF1|
|Target/Specificity||This EAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-85 amino acids from the Central region of human EAF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EAF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.|
|Cellular Location||Nucleus speckle. Nucleus, Cajal body|
|Tissue Location||Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus|
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Provided below are standard protocols that you may find useful for product applications.
EAF1 acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
Wan, X., et al. PLoS ONE 5 (2), E9118 (2010) :
Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Xiao, W., et al. Prostate 66(1):1-12(2006)
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