|Application ||WB, E|
|Other Accession||Q9D4C5, NP_149074.3|
|Calculated MW||29042 Da|
|Antigen Region||58-85 aa|
|Other Names||ELL-associated factor 1, EAF1|
|Target/Specificity||This EAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-85 amino acids from the Central region of human EAF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EAF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.|
|Cellular Location||Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with ELL to nuclear speckles. Also localized to Cajal (coiled) bodies|
|Tissue Location||Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
EAF1 acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
Wan, X., et al. PLoS ONE 5 (2), E9118 (2010) :
Jiang, F., et al. Cancer Lett. 253(2):265-272(2007)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Xiao, W., et al. Prostate 66(1):1-12(2006)
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