|Application ||WB, E|
|Calculated MW||37718 Da|
|Antigen Region||192-219 aa|
|Other Names||Glycerophosphodiester phosphodiesterase 1, Membrane-interacting protein of RGS16, RGS16-interacting membrane protein, GDE1, MIR16|
|Target/Specificity||This GDE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human GDE1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GDE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity).|
|Cellular Location||Cytoplasm. Membrane; Multi-pass membrane protein Note=Perinuclear vesicles and cell membrane.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
GDE1 has glycerophosphoinositol phosphodiesterase activity. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity).
Zhang, X., et al. Cancer Res. 70(18):7176-7186(2010)
Corthals, S.L., et al. Leuk. Res. 34(5):677-681(2010)
Simon, G.M., et al. J. Biol. Chem. 283(14):9341-9349(2008)
Ma, J., et al. Atherosclerosis 191(1):63-72(2007)
Bachmann, A.S., et al. Gene 371(1):144-153(2006)
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