|Application ||WB, E|
|Calculated MW||22764 Da|
|Antigen Region||96-123 aa|
|Other Names||Myosin light chain 6B, Myosin light chain 1 slow-twitch muscle A isoform, MLC1sa, Smooth muscle and nonmuscle myosin light chain alkali 6B, MYL6B, MLC1SA|
|Target/Specificity||This MYL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-123 amino acids from the Central region of human MYL6B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYL6B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory light chain of myosin. Does not bind calcium.|
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Provided below are standard protocols that you may find useful for product applications.
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.
Pathmanathan, S., et al. Mol. Cell. Biochem. 318 (1-2), 43-51 (2008) :
Coureux, P.D., et al. EMBO J. 23(23):4527-4537(2004)
Webb, R.C. Adv Physiol Educ 27 (1-4), 201-206 (2003) :
Komiyama, M., et al. J. Cell. Sci. 109 (PT 8), 2089-2099 (1996) :
Hailstones, D.L., et al. Mol. Cell. Biol. 10(3):1095-1104(1990)
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