UTP11L Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9Y3A2 |
Other Accession | Q8R5K5, NP_057121.2 |
Reactivity | Human |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 30447 Da |
Antigen Region | 227-253 aa |
Gene ID | 51118 |
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Other Names | Probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11, UTP11-like protein, UTP11L |
Target/Specificity | This UTP11L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-253 amino acids from the C-terminal region of human UTP11L. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | UTP11L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | UTP11 (HGNC:24329) |
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Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. |
Cellular Location | Nucleus, nucleolus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
UTP11L is involved in nucleolar processing of pre-18S ribosomal RNA (By similarity).
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Heese, K., et al. Neuroscience 116(2):321-324(2003)
Andersen, J.S., et al. Curr. Biol. 12(1):1-11(2002)
Heese, K., et al. Eur. J. Neurosci. 15(1):79-86(2002)
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