|Application ||WB, E|
|Calculated MW||80698 Da|
|Antigen Region||132-158 aa|
|Other Names||Calcium-responsive transcription factor, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, CaRF, Testis development protein NYD-SP24, CARF, ALS2CR8|
|Target/Specificity||This ALS2CR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-158 amino acids from the N-terminal region of human ALS2CR8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ALS2CR8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ALS2CR8 may be a transcription factor (By similarity).
Cheung, C.T., et al. Mech. Ageing Dev. 130 (1-2), 18-23 (2009) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Hasan, M.K., et al. J. Biol. Chem. 277(40):37765-37770(2002)
Tao, X., et al. Neuron 33(3):383-395(2002)
Hadano, S., et al. Nat. Genet. 29(2):166-173(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.