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ALS2CR8 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ALS2CR8 Antibody (N-term) AP18673a
    ALS2CR8 Antibody (N-term) (Cat. #AP18673a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ALS2CR8 antibody detected the ALS2CR8 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N187
Other Accession NP_001098056.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 80698 Da
Antigen Region 132-158 aa
Additional Information
Gene ID 79800
Other Names Calcium-responsive transcription factor, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein, Calcium-response factor, CaRF, Testis development protein NYD-SP24, CARF, ALS2CR8
Target/Specificity This ALS2CR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-158 amino acids from the N-terminal region of human ALS2CR8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALS2CR8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CARF
Synonyms ALS2CR8
Function Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

ALS2CR8 may be a transcription factor (By similarity).

References

Cheung, C.T., et al. Mech. Ageing Dev. 130 (1-2), 18-23 (2009) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Hasan, M.K., et al. J. Biol. Chem. 277(40):37765-37770(2002)
Tao, X., et al. Neuron 33(3):383-395(2002)
Hadano, S., et al. Nat. Genet. 29(2):166-173(2001)

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$ 365.00
$ 140.00
Cat# AP18673a
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