|Application ||WB, E|
|Other Accession||Q9WUM4, NP_055140.1|
|Calculated MW||53249 Da|
|Antigen Region||377-403 aa|
|Other Names||Coronin-1C, Coronin-3, hCRNN4, CORO1C, CRN2, CRNN4|
|Target/Specificity||This CORO1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-403 amino acids from the C-terminal region of human CORO1C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CORO1C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in cytokinesis, motility, and signal transduction.|
|Cellular Location||Cell membrane. Cell projection, lamellipodium Cytoplasm, cytoskeleton. Note=All isoforms localize in a diffuse and punctate pattern in the cytosol and are highly enriched in F-actin-rich areas. Isoform 3 colocalizes with the thin filaments of the sarcomere and with the postsynaptic area and the junctional sarcoplasm of motor end plates|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation.
Luan, S.L., et al. J. Pathol. 222(2):166-179(2010)
Wu, L., et al. Zhonghua Gan Zang Bing Za Zhi 18(7):516-519(2010)
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Samarin, S.N., et al. Biochem. Biophys. Res. Commun. 391(1):394-400(2010)
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