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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HOXD8 Antibody (C-term)   

HOXD8 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • IF - HOXD8 Antibody (C-term) AP18731B
    Fluorescent image of HUVEC cell stained with HOXD8 Antibody (C-term)(Cat#AP18731b).HUVEC cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HOXD8 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃).HOXD8 immunoreactivity is localized to Nucleus significantly.
  • WB - HOXD8 Antibody (C-term) AP18731B
    HOXD8 Antibody (C-term)(Cat. #AP18731b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the HOXD8 antibody detected the HOXD8 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13378
Other Accession NP_062458.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31911 Da
Antigen Region 243-270 aa
Additional Information
Gene ID 3234
Other Names Homeobox protein Hox-D8, Homeobox protein Hox-4E, Homeobox protein Hox-54, HOXD8, HOX4E
Target/Specificity This HOXD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-270 amino acids from the C-terminal region of human HOXD8.
Dilution IF~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHOXD8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXD8
Synonyms HOX4E
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function.


Ester, A.R., et al. Am. J. Med. Genet. A 149A (12), 2745-2752 (2009) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Harada, K., et al. J. Cell. Sci. 122 (PT 21), 3923-3930 (2009) :
Goodman, F.R. Am. J. Med. Genet. 112(3):256-265(2002)
Kosaki, K., et al. Teratology 65(2):50-62(2002)

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$ 295.00
$ 99.00
Cat# AP18731B
(40 western blots)
Availability: In Stock
Bulk Size
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