|Application ||WB, E|
|Other Accession||Q8BGA3, NP_056379.1|
|Calculated MW||59076 Da|
|Antigen Region||465-491 aa|
|Other Names||Leucine-rich repeat transmembrane neuronal protein 2, Leucine-rich repeat neuronal 2 protein, LRRTM2, KIAA0416, LRRN2|
|Target/Specificity||This LRRTM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-491 amino acids from the C-terminal region of human LRRTM2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRRTM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein Note=Localized to excitatory synapses.|
|Tissue Location||Expressed in neuronal tissues.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
LRRTM2 may play a role in the development and maintenance of the vertebrate nervous system.
Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) :
Lauren, J., et al. Genomics 81(4):411-421(2003)
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