|Application ||WB, E|
|Calculated MW||30433 Da|
|Antigen Region||75-104 aa|
|Other Names||Sorting nexin-11, SNX11|
|Target/Specificity||This SNX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human SNX11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SNX11 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes.|
|Cellular Location||Membrane; Peripheral membrane protein; Cytoplasmic side. Endosome|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. This gene results in two transcript variants differing in the 5' UTR, but encoding the same protein.
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Teasdale, R.D., et al. Biochem. J. 358 (PT 1), 7-16 (2001) :
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