|Application ||WB, E|
|Calculated MW||104334 Da|
|Antigen Region||1-30 aa|
|Other Names||Neutral alpha-glucosidase C, GANC|
|Target/Specificity||This GANC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GANC.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GANC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has alpha-glucosidase activity.|
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Provided below are standard protocols that you may find useful for product applications.
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes.
Oba-Shinjo, S.M., et al. J. Neurol. 256(11):1881-1890(2009)
Kawabata, Y., et al. FEBS Lett. 555(3):623-630(2003)
Dgany, O., et al. Am. J. Hum. Genet. 71(6):1467-1474(2002)
Hirschhorn, R., et al. Proc. Natl. Acad. Sci. U.S.A. 99(21):13642-13646(2002)
Usuki, F., et al. Muscle Nerve 11(4):365-371(1988)
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