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PHLDA1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WV24 |
| Other Accession | NP_031376.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45016 Da |
| Antigen Region | 23-49 aa |
| Gene ID | 22822 |
|---|---|
| Other Names | Pleckstrin homology-like domain family A member 1, Apoptosis-associated nuclear protein, Proline- and glutamine-rich protein, PQ-rich protein, PQR protein, Proline- and histidine-rich protein, T-cell death-associated gene 51 protein, PHLDA1, PHRIP, TDAG51 |
| Target/Specificity | This PHLDA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PHLDA1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PHLDA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PHLDA1 |
|---|---|
| Synonyms | PHRIP, TDAG51 |
| Function | Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. |
| Cellular Location | Cytoplasm. Cytoplasmic vesicle. Nucleus, nucleolus. Note=Colocalizes with intracellular vesicles. |
| Tissue Location | Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Marchiori, A.C., et al. Braz. J. Med. Biol. Res. 41(7):579-582(2008)
Nagai, M.A., et al. Breast Cancer Res. Treat. 106(1):49-56(2007)
Xi, Z.Q., et al. Neurosci. Lett. 425(1):53-58(2007)
Meier-Noorden, M., et al. Gene 338(2):197-207(2004)
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