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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CLEC2D Antibody (Center)   

CLEC2D Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CLEC2D Antibody (Center) AP18951c
    CLEC2D Antibody (Center) (Cat. #AP18951c) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the CLEC2D antibody detected the CLEC2D protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHP7
Other Accession NP_001004419.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21849 Da
Antigen Region 109-137 aa
Additional Information
Gene ID 29121
Other Names C-type lectin domain family 2 member D, Lectin-like NK cell receptor, Lectin-like transcript 1, LLT-1, Osteoclast inhibitory lectin, CLEC2D, CLAX, LLT1, OCIL
Target/Specificity This CLEC2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the Central region of human CLEC2D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLEC2D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CLAX, LLT1, OCIL
Function Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon- gamma. Binds high molecular weight sulfated glycosaminoglycans.
Cellular Location Cell membrane; Single-pass type II membrane protein. Cell surface Isoform 4: Endoplasmic reticulum.
Tissue Location Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells
Research Areas
Citations (0)

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This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.


Germain, C., et al. J. Biol. Chem. (2010) In press :
Bambard, N.D., et al. Scand. J. Immunol. 71(3):210-219(2010)
Skinningsrud, B., et al. J. Clin. Endocrinol. Metab. 93(9):3310-3317(2008)
Rosen, D.B., et al. J. Immunol. 180(10):6508-6517(2008)
Pineda, B., et al. Calcif. Tissue Int. 82(5):348-353(2008)

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$ 295.00
$ 99.00
Cat# AP18951c
(40 western blots)
Availability: In Stock
Bulk Size
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