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MIER1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MIER1 Antibody (Center) AP18957C
    MIER1 Antibody (Center) (Cat. #AP18957c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MIER1 antibody detected the MIER1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N108
Other Accession Q5UAK0, NP_001071169.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57983 Da
Antigen Region 214-242 aa
Additional Information
Gene ID 57708
Other Names Mesoderm induction early response protein 1, Early response 1, Er1, Mi-er1, hMi-er1, MIER1, KIAA1610
Target/Specificity This MIER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the Central region of human MIER1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMIER1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MIER1
Synonyms KIAA1610
Function Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing.
Cellular Location Isoform 1: Nucleus. Isoform 3: Nucleus. Isoform 5: Cytoplasm.
Tissue Location Ubiquitously expressed, but at very low levels. However, consistent level of expression are observed in heart, testis, thyroid, ovary and adrenal gland. Transcripts are up-regulated in breast carcinoma cell lines and tumor
Citations (0)

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Transcriptional repressor of a number of genes including Sp1 target genes.


McCarthy, P.L., et al. Br. J. Cancer 99(4):639-646(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

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$ 295.00
$ 99.00
Cat# AP18957C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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