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KCNG2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UJ96 |
| Other Accession | NP_036415.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51240 Da |
| Antigen Region | 149-177 aa |
| Gene ID | 26251 |
|---|---|
| Other Names | Potassium voltage-gated channel subfamily G member 2, Cardiac potassium channel subunit, Voltage-gated potassium channel subunit Kv62, KCNG2, KCNF2 |
| Target/Specificity | This KCNG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-177 amino acids from the Central region of human KCNG2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KCNG2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNG2 |
|---|---|
| Synonyms | KCNF2 |
| Function | Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values. |
| Cellular Location | Membrane; Multi-pass membrane protein. |
| Tissue Location | Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Detected at low levels in brain, lung and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member is a gamma subunit of the voltage-gated potassium channel. The delayed-rectifier type channels containing this subunit may contribute to cardiac action potential repolarization. [provided by RefSeq].
References
Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)
Zhu, X.R., et al. Recept. Channels 6(5):337-350(1999)
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