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PAIP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PAIP1 Antibody (N-term) AP19021a
    PAIP1 Antibody (N-term) (Cat. #AP19021a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PAIP1 antibody detected the PAIP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H074
Other Accession NP_006442.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53525 Da
Antigen Region 23-49 aa
Additional Information
Gene ID 10605
Other Names Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1, PAIP1
Target/Specificity This PAIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-49 amino acids from the N-terminal region of human PAIP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAIP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAIP1
Function Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
Cellular Location Cytoplasm.
Citations (0)

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The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.


Kanaan, A.S., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 10), 1060-1064 (2009) :
Martineau, Y., et al. Mol. Cell. Biol. 28(21):6658-6667(2008)
Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :
Roy, G., et al. Mol. Cell. Biol. 22(11):3769-3782(2002)
Deo, R.C., et al. Proc. Natl. Acad. Sci. U.S.A. 98(8):4414-4419(2001)

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$ 295.00
$ 99.00
Cat# AP19021a
(40 western blots)
Availability: In Stock
Bulk Size
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