|Application ||WB, E|
|Other Accession||P84586, D4AE41, Q91VM5, NP_001156008.1|
|Calculated MW||42142 Da|
|Antigen Region||237-263 aa|
|Other Names||RNA binding motif protein, X-linked-like-1, Heterogeneous nuclear ribonucleoprotein G-like 1, RBMXL1|
|Target/Specificity||This RBMXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the Central region of human RBMXL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RBMXL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein which may be involved in pre-mRNA splicing.|
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Provided below are standard protocols that you may find useful for product applications.
This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants.
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Marques, A.C., et al. PLoS Biol. 3 (11), E357 (2005) :
Emerson, J.J., et al. Science 303(5657):537-540(2004)
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