|Application ||WB, E|
|Other Accession||Q15415, A6NEQ0, P0DJD4, A6NDE4, P0DJD3, NP_001006120.2|
|Calculated MW||55775 Da|
|Antigen Region||444-470 aa|
|Other Names||RNA-binding motif protein, Y chromosome, family 1 member D, RBMY1D|
|Target/Specificity||This RBMY1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-470 amino acids from the C-terminal region of human RBMY1D.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RBMY1D Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA splicing in the testis.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].
Tsuei, D.J., et al. Oncogene 23(34):5815-5822(2004)
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
Chai, N.N., et al. Genomics 49(2):283-289(1998)
Prosser, J., et al. Mamm. Genome 7(11):835-842(1996)
Ma, K., et al. Cell 75(7):1287-1295(1993)
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