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TIMM50 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TIMM50 Antibody (N-term) AP19064a
    TIMM50 Antibody (N-term) (Cat. #AP19064a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TIMM50 antibody detected the TIMM50 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q3ZCQ8
Other Accession NP_001001563.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39646 Da
Antigen Region 74-104 aa
Additional Information
Gene ID 92609
Other Names Mitochondrial import inner membrane translocase subunit TIM50, TIMM50, TIM50
Target/Specificity This TIMM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human TIMM50.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTIMM50 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMM50
Synonyms TIM50
Function Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
Cellular Location Mitochondrion inner membrane; Single-pass membrane protein
Tissue Location Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level)
Research Areas
Citations (0)

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Background

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.

References

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Xu, H., et al. BMC Cell Biol. 6 (1), 29 (2005) :
Guo, Y., et al. J. Biol. Chem. 279(23):24813-24825(2004)
Yuryev, A., et al. Genomics 81(2):112-125(2003)
Yamamoto, H., et al. Cell 111(4):519-528(2002)

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$ 295.00
$ 99.00
Cat# AP19064a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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