|Application ||WB, E|
|Other Accession||Q4R5C7, NP_003125.3|
|Calculated MW||14570 Da|
|Antigen Region||28-55 aa|
|Other Names||Signal recognition particle 14 kDa protein, SRP14, 18 kDa Alu RNA-binding protein, SRP14|
|Target/Specificity||This SRP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-55 amino acids from the Central region of human SRP14.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SRP14 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.|
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Provided below are standard protocols that you may find useful for product applications.
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Mary, C., et al. RNA 16(5):969-979(2010)
Lakkaraju, A.K., et al. Cell 133(3):440-451(2008)
Yoshida, M., et al. Mol. Pharmacol. 73(3):987-994(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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