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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PES1 Antibody (C-term)   

PES1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PES1 Antibody (C-term) AP19122b
    PES1 Antibody (C-term) (Cat. #AP19122b) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the PES1 antibody detected the PES1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00541
Other Accession NP_055118.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68003 Da
Antigen Region 549-578 aa
Additional Information
Gene ID 23481
Other Names Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028}, PES1 {ECO:0000255|HAMAP-Rule:MF_03028}
Target/Specificity This PES1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the C-terminal region of human PES1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPES1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PES1 {ECO:0000255|HAMAP-Rule:MF_03028}
Function Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Cellular Location Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Note=Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli {ECO:0000255|HAMAP-Rule:MF_03028}
Tissue Location Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin
Research Areas
Citations (0)

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This gene encodes a protein that is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product. The gene plays a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression.


Zhang, J., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(12):991-997(2009)
Li, J., et al. Cancer Sci. 100(12):2255-2260(2009)
Rikova, K., et al. Cell 131(6):1190-1203(2007)
Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007)
Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006)

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$ 295.00
$ 99.00
Cat# AP19122b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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