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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RHPN2 Antibody (Center)   

RHPN2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RHPN2 Antibody (Center) AP19291C
    RHPN2 Antibody (Center)(Cat. #AP19291c) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the RHPN2 antibody detected the RHPN2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IUC4
Other Accession NP_149094.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 76993 Da
Antigen Region 352-380 aa
Additional Information
Gene ID 85415
Other Names Rhophilin-2, 76 kDa RhoB effector protein, GTP-Rho-binding protein 2, p76RBE, RHPN2
Target/Specificity This RHPN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from the Central region of human RHPN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRHPN2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RHPN2
Function Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity.
Cellular Location Cytoplasm, perinuclear region
Tissue Location Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver
Research Areas
Citations (0)

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This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins. The encoded protein binds both GTP- and GDP-bound RhoA and GTP-bound RhoB and may be involved in the organization of the actin cytoskeleton. [provided by RefSeq].


Abuli, A., et al. Gastroenterology 139(3):788-796(2010)
von Holst, S., et al. Br. J. Cancer 103(4):575-580(2010)
Kupfer, S.S., et al. Gastroenterology (2010) In press :
Xiong, F., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1855-1861(2010)
Hawken, S.J., et al. Hum. Genet. 128(1):89-101(2010)

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$ 295.00
$ 99.00
Cat# AP19291C
(40 western blots)
Availability: In Stock
Bulk Size
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