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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ENTPD5 Antibody (C-term)   

ENTPD5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ENTPD5 Antibody (C-term) AP19295b
    ENTPD5 Antibody (C-term)(Cat. #AP19295b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the ENTPD5 antibody detected the ENTPD5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75356
Other Accession NP_001240.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47517 Da
Antigen Region 333-362 aa
Additional Information
Gene ID 957
Other Names Ectonucleoside triphosphate diphosphohydrolase 5, NTPDase 5, CD39 antigen-like 4, ER-UDPase, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5, ENTPD5, CD39L4, PCPH
Target/Specificity This ENTPD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-362 amino acids from the C-terminal region of human ENTPD5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsENTPD5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD39L4, PCPH
Function Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
Cellular Location Endoplasmic reticulum. Secreted
Tissue Location Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues
Research Areas
Citations (0)

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The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.


Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010)
Villar, J., et al. Cancer Res. 69(1):102-110(2009)
Villar, J., et al. Cancer Res. 67(22):10859-10868(2007)
Regadera, J., et al. Int. J. Oncol. 28(3):595-604(2006)
Liu, T., et al. J. Proteome Res. 4(6):2070-2080(2005)

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$ 295.00
$ 99.00
Cat# AP19295b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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