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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SEPT12 Antibody (Center)   

SEPT12 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPT12 Antibody (Center) AP19298c
    SEPT12 Antibody (Center)(Cat. #AP19298c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SEPT12 antibody detected the SEPT12 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IYM1
Other Accession NP_001147930.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 40748 Da
Antigen Region 218-244 aa
Additional Information
Gene ID 124404
Other Names Septin-12, SEPT12
Target/Specificity This SEPT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-244 amino acids from the Central region of human SEPT12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPT12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPT12
Function Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell projection, cilium, flagellum. Note=At interphase, forms a filamentous structure in the cytoplasm. During anaphase, translocates to the central spindle region and to the midbody during cytokinesis. Found in the sperm annulus
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Septins, such as SEPT12, are conserved GTP-binding proteins that function as dynamic, regulatable scaffolds for the recruitment of other proteins. They are involved in membrane dynamics, vesicle trafficking, apoptosis, and cytoskeleton remodeling, as well as infection, neurodegeneration, and neoplasia (Hall et al., 2005 [PubMed 15915442]).


Lin, Y.H., et al. Am. J. Pathol. 174(5):1857-1868(2009)
Ding, X., et al. Mol. Cells 25(3):385-389(2008)
Ding, X., et al. J. Biochem. Mol. Biol. 40(6):973-978(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hall, P.A., et al. J. Pathol. 206(3):269-278(2005)

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$ 295.00
$ 99.00
Cat# AP19298c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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