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>   home   >   Products   >   Primary Antibodies   >   SMG5 Antibody (C-term)   

SMG5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SMG5 Antibody (C-term) AP19361B
    SMG5 Antibody (C-term)(Cat. #AP19361b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the SMG5 antibody detected the SMG5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UPR3
Other Accession Q6ZPY2, NP_056142.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 113928 Da
Antigen Region 912-941 aa
Additional Information
Gene ID 23381
Other Names Protein SMG5, EST1-like protein B, LPTS-RP1, LPTS-interacting protein, SMG-5 homolog, hSMG-5, SMG5, EST1B, KIAA1089
Target/Specificity This SMG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-941 amino acids from the C-terminal region of human SMG5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSMG5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMG5
Synonyms EST1B, KIAA1089
Function Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic, and nuclear. Shuttles between nucleus and cytoplasm Detected in cytoplasmic mRNA decay bodies
Tissue Location Ubiquitous.
Citations (0)

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SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).


Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Glavan, F., et al. EMBO J. 25(21):5117-5125(2006)
Lee, H., et al. Mol. Cell. Biol. 26(14):5259-5269(2006)
Azzalin, C.M., et al. Curr. Biol. 16(4):433-439(2006)
Unterholzner, L., et al. Mol. Cell 16(4):587-596(2004)

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$ 295.00
$ 99.00
Cat# AP19361B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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