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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TMPRSS6 Antibody(N-term)   

TMPRSS6 Antibody(N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TMPRSS6 Antibody(N-term) AP19372a
    TMPRSS6 Antibody (N-term)(Cat. #AP19372a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TMPRSS6 antibody detected the TMPRSS6 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IU80
Other Accession NP_705837.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 90000 Da
Antigen Region 85-114 aa
Additional Information
Gene ID 164656
Other Names Transmembrane protease serine 6, 3421-, Matriptase-2, TMPRSS6
Target/Specificity This TMPRSS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human TMPRSS6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMPRSS6 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HFE2, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.
Cellular Location Cell membrane; Single- pass type II membrane protein. Note=The processed, activated two- chains form is released in the extracellular space
Tissue Location Liver specific..
Research Areas
Citations (0)

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The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.


Altamura, S., et al. Biochem. J. 431(3):363-371(2010)
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
De Falco, L., et al. Hum. Mutat. 31 (5), E1390-E1405 (2010) :
Tanaka, T., et al. Blood 115(1):94-96(2010)
Lee, P. Acta Haematol. 122 (2-3), 87-96 (2009) :

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$ 295.00
$ 99.00
Cat# AP19372a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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