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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Mouse Ephb6 Antibody(Center)   

Mouse Ephb6 Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Ephb6 Antibody(Center) AP19421c
    Western blot analysis of lysate from mouse thymus tissue lysate, using Mouse Ephb6 Antibody (Center)(Cat. #AP19421c). AP19421c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • WB - Mouse Ephb6 Antibody(Center) AP19421c
    Western blot analysis of lysate from mouse thymus tissue lysate, using Mouse Ephb6 Antibody (Center)(Cat. #AP19421c). AP19421c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O08644
Other Accession P0C0K7, O15197, NP_001139823.1
Reactivity Mouse
Predicted Human, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 110107 Da
Antigen Region 503-530 aa
Additional Information
Gene ID 13848
Other Names Ephrin type-B receptor 6, MEP, Tyrosine-protein kinase-defective receptor EPH-6, Ephb6, Cekl
Target/Specificity This Mouse Ephb6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-530 amino acids from the Central region of mouse Ephb6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Ephb6 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ephb6
Synonyms Cekl
Function Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted.
Tissue Location High level in thymus, and brain. Very low levels of expression in kidney, lung, liver, bone marrow, skeletal muscle, spleen from 2 week old and adult mice, heart, testes and embryonic stem cells.
Research Areas
Citations (0)

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Background

Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).

References

Islam, S., et al. Dig. Dis. Sci. 55(9):2478-2488(2010)
Lieben, L., et al. Bone 47(2):301-308(2010)
Mordan-McCombs, S., et al. J. Steroid Biochem. Mol. Biol. 121 (1-2), 368-371 (2010) :
Zirzow, S., et al. Dev. Biol. 336(2):145-155(2009)
Chou, S.J., et al. Nat. Neurosci. 12(11):1381-1389(2009)

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$ 295.00
$ 99.00
Cat# AP19421c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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