LGI3 Antibody(Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
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Primary Accession | Q8N145 |
Other Accession | Q8K406, Q4R4H3, NP_644807.1 |
Reactivity | Human |
Predicted | Monkey, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 61704 Da |
Antigen Region | 310-338 aa |
Gene ID | 203190 |
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Other Names | Leucine-rich repeat LGI family member 3, LGI1-like protein 4, Leucine-rich glioma-inactivated protein 3, LGI3, LGIL4 |
Target/Specificity | This LGI3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human LGI3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LGI3 Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LGI3 |
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Synonyms | LGIL4 |
Function | May participate in the regulation of neuronal exocytosis. |
Cellular Location | Secreted. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q8K406}. Synapse, synaptosome {ECO:0000250|UniProtKB:Q8K406}. Cell projection, axon {ECO:0000250|UniProtKB:Q8K406}. Note=Found in the synaptosomal membrane fraction. Within peripheral myelinated axons, LGI3 is highly expressed at the juxtaparanodal membrane and colocalizes with the voltage-gated potassium channels Kv1.1 (KCNA1) and Kv1.2 (KCNA2), and with CNTNAP2, DLG4, ADAM22 and ADAM23 (By similarity) {ECO:0000250|UniProtKB:Q8K406} |
Tissue Location | Widely expressed, with highest levels in brain and lung. |

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