|Application ||WB, E|
|Calculated MW||68976 Da|
|Antigen Region||571-602 aa|
|Other Names||Podocan, PODN, SLRR5A|
|Target/Specificity||This PODN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-602 amino acids from the C-terminal region of human PODN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PODN Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates cell proliferation and cell migration.|
|Cellular Location||Isoform 1: Secreted, extracellular space, extracellular matrix Isoform 3: Cytoplasm.|
|Tissue Location||Kidney, heart, liver, pancreas and vascular smooth muscle cells. Also detected in aortic intima (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Negatively regulates cell proliferation and cell migration.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Shimizu-Hirota, R., et al. FEBS Lett. 563 (1-3), 69-74 (2004) :
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Ross, M.D., et al. J. Biol. Chem. 278(35):33248-33255(2003)
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