|Application ||WB, E|
|Calculated MW||73525 Da|
|Antigen Region||155-183 aa|
|Other Names||Zinc finger protein 185, LIM domain protein ZNF185, P1-A, ZNF185|
|Target/Specificity||This ZNF185 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the N-terminal region of human ZNF185.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF185 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the regulation of cellular proliferation and/or differentiation.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, focal adhesion|
|Tissue Location||Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood|
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Provided below are standard protocols that you may find useful for product applications.
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Zhang, J.S., et al. Oncogene 26(1):111-122(2007)
Medina, P.P., et al. Hum. Mol. Genet. 14(7):973-982(2005)
Vanaja, D.K., et al. Cancer Res. 63(14):3877-3882(2003)
Mallon, A.M., et al. Genome Res. 10(6):758-775(2000)
Heiss, N.S., et al. Genomics 43(3):329-338(1997)
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