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PRPS1L1 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P21108 |
| Other Accession | NP_787082.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 34839 Da |
| Antigen Region | 77-106 aa |
| Gene ID | 221823 |
|---|---|
| Other Names | Ribose-phosphate pyrophosphokinase 3, Phosphoribosyl pyrophosphate synthase 1-like 1, PRPS1-like 1, Phosphoribosyl pyrophosphate synthase III, PRS-III, PRPS1L1, PRPS3, PRPSL |
| Target/Specificity | This PRPS1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the N-terminal region of human PRPS1L1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PRPS1L1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PRPS1L1 |
|---|---|
| Synonyms | PRPS3, PRPSL |
| Function | Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. |
| Tissue Location | Testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates exclusively at a non-AUG (ACG) codon. [provided by RefSeq].
References
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Taira, M., et al. J. Biol. Chem. 265(27):16491-16497(1990)
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