|Application ||WB, E|
|Calculated MW||59588 Da|
|Antigen Region||403-431 aa|
|Other Names||Lymphoid-restricted membrane protein, Protein Jaw1, Processed lymphoid-restricted membrane protein, Lrmp, Jaw1|
|Target/Specificity||This Mouse Lrmp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403-431 amino acids from the C-terminal region of mouse Lrmp.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Lrmp Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.|
|Cellular Location||Processed lymphoid-restricted membrane protein: Cytoplasm|
|Tissue Location||Spleen and thymus. Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in circumvallate (CV), foliate (FL) and fungiform (FF) taste papillae cells of the tongue epithelium.|
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The function of this protein is unknown.
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