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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PDE6H Antibody(Center)   

PDE6H Antibody(Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PDE6H Antibody(Center) AP19799c
    PDE6H Antibody (Center) (Cat. #AP19799c) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the PDE6H antibody detected the PDE6H protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13956
Other Accession P09174, P18545, P04972, P61250, P61249, P22571, NP_006196.1
Reactivity Mouse
Predicted Bovine, Rat, Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 9074 Da
Antigen Region 4-33 aa
Additional Information
Gene ID 5149
Other Names Retinal cone rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase subunit gamma, GMP-PDE gamma, PDE6H
Target/Specificity This PDE6H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-33 amino acids from the Central region of human PDE6H.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPDE6H Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDE6H
Function Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
Research Areas
Citations (0)

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This gene encodes the inhibitory (or gamma) subunit of the cone-specific cGMP phosphodiesterase, which is a tetramer composed of two catalytic chains (alpha and beta), and two inhibitory chains (gamma). It is specifically expressed in the retina, and is involved in the transmission and amplification of the visual signal. Mutations in this gene are associated with retinal cone dystrophy type 3A (RCD3A).


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Piri, N., et al. Ophthalmology 112(1):159-166(2005)
Kajimura, N., et al. J. Struct. Biol. 139(1):27-38(2002)
Shimizu-Matsumoto, A., et al. Genomics 32(1):121-124(1996)

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Cat# AP19799c
(40 western blots)
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