|Application ||WB, IHC-P, E|
|Calculated MW||54939 Da|
|Antigen Region||141-170 aa|
|Other Names||Zinc finger protein 395, HD-regulating factor 2, HDRF-2, Huntington disease gene regulatory region-binding protein 2, HD gene regulatory region-binding protein 2, HDBP-2, Papillomavirus regulatory factor 1, PRF-1, Papillomavirus-binding factor, ZNF395, HDBP2, PBF|
|Target/Specificity||This HDBP2(HDRF-2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the Central region of human HDBP2(HDRF-2).|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HDBP2(HDRF-2) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in papillomavirus genes transcription.|
|Cellular Location||Cytoplasm. Nucleus. Note=May shuttle between nucleus and cytoplasm|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Papillomavirus Regulatory Factor 1/HDBP2 is a novel transcription factor shuttling between nucleus and cytoplasm and binds to the specific GCCGGCG, which is an essential cis-element for Huntington's disease gene expression.
Tanaka,K., J. Biol. Chem. 279 (8), 7275-7286 (2004)
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