|Application ||WB, E|
|Calculated MW||17883 Da|
|Antigen Region||84-112 aa|
|Other Names||Protein GAPT, Growth factor receptor-bound protein 2-binding adapter protein, transmembrane, GAPT, C5orf29|
|Target/Specificity||This GAPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-112 amino acids from the Central region of human GAPT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAPT Antibody(Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity).|
|Cellular Location||Cell membrane; Single-pass membrane protein|
|Tissue Location||Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells.|
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Negatively regulates B-cell proliferation following stimulation through the B-cell receptor. May play an important role in maintenance of marginal zone (MZ) B-cells (By similarity).
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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