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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ZMPSTE24 Antibody (C-term)   

ZMPSTE24 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZMPSTE24 Antibody (C-term) AP19939b
    ZMPSTE24 Antibody (C-term) (Cat. #AP19939b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ZMPSTE24 antibody detected the ZMPSTE24 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75844
Other Accession Q80W54, NP_005848.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54813 Da
Antigen Region 404-433 aa
Additional Information
Gene ID 10269
Other Names CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Target/Specificity This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-433 amino acids from the C-terminal region of human ZMPSTE24.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZMPSTE24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FACE1, STE24
Function Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein
Tissue Location Widely expressed. High levels in kidney, prostate, testis and ovary
Research Areas
Citations (0)

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This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Miner, J.H. Am. J. Med. Genet. A 152A (8), 2140-2141 (2010) :
Smigiel, R., et al. Am. J. Med. Genet. A 152A (2), 447-452 (2010) :
Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

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$ 295.00
$ 99.00
Cat# AP19939b
(40 western blots)
Availability: In Stock
Bulk Size
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