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TES Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UGI8 |
| Other Accession | Q2QLE3, Q90YH9, Q2YDE9, NP_690042.1, Q2QLB2, Q09YJ2 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Horse, Pig, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47996 Da |
| Antigen Region | 41-70 aa |
| Gene ID | 26136 |
|---|---|
| Other Names | Testin, TESS, TES |
| Target/Specificity | This TES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TES. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TES Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TES |
|---|---|
| Function | Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. |
| Cellular Location | Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. Multiple protein isoforms are encoded by transcript variants of this gene.
References
Qiu, H., et al. Cancer Sci. 101(5):1255-1260(2010)
Gunduz, E., et al. Arch. Otolaryngol. Head Neck Surg. 135(3):254-260(2009)
Zhong, Y., et al. Mol. Cell. Biochem. 320 (1-2), 85-92 (2009) :
Huang, W., et al. Ai Zheng 27(9):984-988(2008)
Boeda, B., et al. Mol. Cell 28(6):1071-1082(2007)
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