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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CDKN3 Antibody (N-term)   

CDKN3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDKN3 Antibody (N-term) AP20057A
    CDKN3 Antibody (N-term) (Cat. #AP20057a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CDKN3 antibody detected the CDKN3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16667
Other Accession NP_005183.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23805 Da
Antigen Region 39-68 aa
Additional Information
Gene ID 1033
Other Names Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase, CDKN3, CDI1, CIP2, KAP
Target/Specificity This CDKN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human CDKN3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDKN3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDKN3
Synonyms CDI1, CIP2, KAP
Function May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Cellular Location Cytoplasm, perinuclear region
Research Areas
Citations (0)

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The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Jiang, R., et al. Int. J. Cancer 126(5):1263-1274(2010)
Okamoto, K., et al. Biochem. Biophys. Res. Commun. 351(1):216-222(2006)
Hsieh, M.J., et al. Biochem. Biophys. Res. Commun. 349(2):573-581(2006)
Chinami, M., et al. J. Biol. Chem. 280(17):17235-17242(2005)

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$ 295.00
$ 99.00
Cat# AP20057A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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