|Application ||WB, E|
|Calculated MW||25225 Da|
|Antigen Region||211-237 aa|
|Other Names||Homeobox D12, isoform CRA_a;HOXD12|
|Target/Specificity||This HOXD12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-237 amino acids from the C-terminal region of human HOXD12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HOXD12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
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