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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KRT86 Antibody (Center)   

KRT86 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KRT86 Antibody (Center) AP20108c
    KRT86 Antibody (Center) (Cat. #AP20108c) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the KRT86 antibody detected the KRT86 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43790
Other Accession Q9Z2T6, P78386, P78385, A4FUZ0, Q14533, Q148H4, A6NCN2, NP_002275.1, P15241, P25691
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53501 Da
Antigen Region 300-327 aa
Additional Information
Gene ID 3892
Other Names Keratin, type II cuticular Hb6, Hair keratin K211, Keratin-86, K86, Type II hair keratin Hb6, Type-II keratin Kb26, KRT86, KRTHB6
Target/Specificity This KRT86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human KRT86.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKRT86 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT86
Synonyms KRTHB6
Tissue Location Synthesis begins slightly higher in the hair shaft than HB1 and HB3 and continues much farther up, ending in the keratogeneous zone.
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.


ZHANG, S.D., et al. Eur J Dermatol 19(5):508-509(2009)
Feng, A.P., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25(2):141-144(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Langbein, L., et al. Int. Rev. Cytol. 243, 1-78 (2005) :

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$ 295.00
$ 99.00
Cat# AP20108c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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