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MEG11 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MEG11 Antibody  (N-term) AP20250a
    MEG11 Antibody (N-term) (Cat. #AP20250a) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the MEG11 antibody detected the MEG11 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession A6BM72
Other Accession Q80T91, NP_115821.2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 110844 Da
Antigen Region 50-79 aa
Additional Information
Gene ID 84465
Other Names Multiple epidermal growth factor-like domains protein 11, Multiple EGF-like domains protein 11, MEGF11, KIAA1781
Target/Specificity This MEG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human MEG11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMEG11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEGF11
Synonyms KIAA1781
Function May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein Basolateral cell membrane; Single- pass type I membrane protein Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10
Research Areas
Citations (0)

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Background

The function of this protein is unknown.

References

Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Suzuki, E., et al. Exp. Cell Res. 313(11):2451-2464(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)

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Cat# AP20250a
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(40 western blots)
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