|Application ||WB, E|
|Other Accession||Q80T91, NP_115821.2|
|Calculated MW||110844 Da|
|Antigen Region||50-79 aa|
|Other Names||Multiple epidermal growth factor-like domains protein 11, Multiple EGF-like domains protein 11, MEGF11, KIAA1781|
|Target/Specificity||This MEG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human MEG11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MEG11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May regulate the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Basolateral cell membrane; Single- pass type I membrane protein Note=Forms an irregular, mosaic-like adhesion pattern in region of the cell that becomes firmely fixed to the substrate. Localized to protruding lamellipodia. Does not localize with MEGF10|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The function of this protein is unknown.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Suzuki, E., et al. Exp. Cell Res. 313(11):2451-2464(2007)
Lim, J., et al. Cell 125(4):801-814(2006)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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