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MTAP Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MTAP Antibody (N-term) AP20271a
    MTAP Antibody (N-term) (Cat. #AP20271a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the MTAP antibody detected the MTAP protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13126
Other Accession Q9CQ65, Q3MHF7, NP_002442.2
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 31236 Da
Antigen Region 8-37 aa
Additional Information
Gene ID 4507
Other Names S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, 24228 {ECO:0000255|HAMAP-Rule:MF_03155}, 5'-methylthioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, MTA phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155}, MTAP {ECO:0000255|HAMAP-Rule:MF_03155}, MTAPase {ECO:0000255|HAMAP-Rule:MF_03155}, MTAP {ECO:0000255|HAMAP-Rule:MF_03155}, MSAP
Target/Specificity This MTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human MTAP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTAP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTAP {ECO:0000255|HAMAP-Rule:MF_03155}
Synonyms MSAP
Function Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates.
Cellular Location Cytoplasm. Nucleus {ECO:0000255|HAMAP- Rule:MF_03155}
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.


Newton-Bishop, J.A., et al. Cancer Epidemiol. Biomarkers Prev. 19(8):2043-2054(2010)
Yang, X.R., et al. Fam. Cancer (2010) In press :
Krasinskas, A.M., et al. Mod. Pathol. 23(4):531-538(2010)
Zhang, Q., et al. Zhonghua Liu Xing Bing Xue Za Zhi 31(1):83-86(2010)
Huang, H.Y., et al. Clin. Cancer Res. 15(22):6963-6972(2009)

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$ 295.00
$ 99.00
Cat# AP20271a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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