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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Camk1d Antibody (N-term)   

Mouse Camk1d Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Camk1d Antibody (N-term) AP20362a
    Mouse Camk1d Antibody (N-term) (Cat. #AP20362a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Mouse Camk1d antibody detected the Mouse Camk1d protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8BW96
Other Accession Q8IU85
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42919 Da
Antigen Region 39-67 aa
Additional Information
Gene ID 227541
Other Names Calcium/calmodulin-dependent protein kinase type 1D, CaM kinase I delta, CaM-KI delta, CaMKI delta, CaM kinase ID, CaMKI-like protein kinase, CKLiK, mCKLiK, Camk1d
Target/Specificity This Mouse Camk1d antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the N-terminal region of mouse Camk1d.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Camk1d Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Camk1d
Function Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine- induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta (By similarity). Isoform 1 but not isoform 2 activates CREB1.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear upon activation.
Tissue Location Expressed ubiquitously with high levels in brain and low levels in kidney. Isoform 2 is highly expressed in brain compared to other tissues. In hematopoietic cell lines predominant expression was detected in T and EC cells
Research Areas
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Background

Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta (By similarity). Isoform 1 but not isoform 2 activates CREB1.

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Cat# AP20362a
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(40 western blots)
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