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PTGER4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • IHC-P - PTGER4 Antibody (Center) AP20451c
    Immunohistochemical analysis of paraffin-embedded H. brain section using PTGER4 Antibody (Center)(Cat#AP20451c). AP20451c was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
  • WB - PTGER4 Antibody (Center) AP20451c
    PTGER4 Antibody (Center) (Cat. #AP20451c) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane).This demonstrates the PTGER4 antibody detected the PTGER4 protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P35408
Other Accession P43114, Q28691, P32240, Q8MJ08
Reactivity Human, Mouse
Predicted Bovine, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53119 Da
Antigen Region 242-269 aa
Additional Information
Gene ID 5734
Other Names Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor, PTGER4, PTGER2
Target/Specificity This PTGER4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the Central region of human PTGER4.
Dilution IHC-P~~1:25
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTGER4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGER4
Synonyms PTGER2
Function Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle
Research Areas
Citations (0)

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Background

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

References

Bastien L., et al. J. Biol. Chem. 269:11873-11877(1994).
An S., et al. Biochem. Biophys. Res. Commun. 197:263-270(1993).
Foord S.M., et al. Genomics 35:182-188(1996).
Mori K., et al. J. Mol. Med. 74:333-336(1996).
Kopatz S.A., et al. Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AP20451c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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