APBB3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O95704 |
Other Accession | O35827, Q8R1C9 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 52585 Da |
Antigen Region | 187-214 aa |
Gene ID | 10307 |
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Other Names | Amyloid beta A4 precursor protein-binding family B member 3, Protein Fe65-like 2, Fe65L2, APBB3, FE65L2 |
Target/Specificity | This APBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-214 amino acids from the Central region of human APBB3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | APBB3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APBB3 (HGNC:20708) |
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Function | May modulate the internalization of amyloid-beta precursor protein. |
Cellular Location | Cytoplasm. Nucleus [Isoform I-245]: Nucleus. |
Tissue Location | Expressed in various tissues, highest expression in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
May modulate the internalization of beta-amyloid precursor protein.
References
Tanahashi H., et al. Neurosci. Lett. 261:143-146(1999).
Tanahashi H., et al. Biochem. Biophys. Res. Commun. 258:385-389(1999).
Mao Y.M., et al. Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Ota T., et al. Nat. Genet. 36:40-45(2004).
Schmutz J., et al. Nature 431:268-274(2004).
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