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CLIC1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - CLIC1 Antibody (Center) AP20511c
    CLIC1 Antibody (Center) (Cat. #AP20511c) western blot analysis in HL-60,MCF-7,Raji,WiDr cell line and human placenta tissue lysates (35ug/lane).This demonstrates the CLIC1 antibody detected the CLIC1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00299
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26923 Da
Antigen Region 136-166 aa
Additional Information
Gene ID 1192
Other Names Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27
Target/Specificity This CLIC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-166 amino acids from the Central region of human CLIC1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCLIC1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLIC1
Synonyms G6, NCC27
Function Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Cellular Location Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain
Tissue Location Expression is prominent in heart, placenta, liver, kidney and pancreas.
Research Areas
Citations (0)

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Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.


Xie T., et al. Genome Res. 13:2621-2636(2003).
Shiina S., et al. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Valenzuela S.M., et al. J. Biol. Chem. 272:12575-12582(1997).
Noh Y.H., et al. Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
Chuang J.Z., et al. J. Neurosci. 19:2919-2928(1999).

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$ 295.00
$ 99.00
Cat# AP20511c
(40 western blots)
Availability: In Stock
Bulk Size
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